Recent findings suggested an association between the use of antiperspirants or make-up and skin microbiota composition. It harbors a microbial habitat that is person-specific and varies considerably across the body surface. The human skin is the most exposed organ to the external environment and represents the first line of defense against external chemical and microbial threats. Representation of the number of samples that were removed (gray) and those retained (blue) after rarefaction at 10,000 threshold. Correlation between specific molecules and bacteria that change over time in armpits of individual 11. Procrustes analysis to correlate the skin microbiome and metabolome over time. Representation of Gram-positive bacteria over time and the molecular features from the shampoo detected on feet. Beauty products applied at one body part might affect other areas of the body, while specific products determine stability versus variability of microflora at each body site. Characterization of Acylcarnitine family members in skin samples. Characterization of bile acids in armpit samples. Characterization of steroids in armpits samples. Longitudinal abundance of bile acids and acylcarnitines in skin samples. Molecular networking to highlight MS/MS spectra found in each body part. Longitudinal impact of ceasing and resuming the use of beauty products on the molecular composition of the skin over time. Beauty product application impacts the molecular and bacterial diversity on skin of 11 individuals while the chemical diversity from personal beauty products used by males and females on T0 is similar. Beauty products ingredients persist on skin of participants.
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